Abstract : Dark neurons assist to utilize neuropathology for understanding the effect of different neurological disorders such as hyperglycemia, dementia, and Alzheimer's disease. This factor assists in identifying the vital signs of disease and the progression process of disease and monitoring transformation in the brain associated with the protein accumulation in the neurotransmitter. The DN has also appeared in the abscess of trauma or the mechanical forces applied in a brain that define diseases related to the central nervous system. This factor reflects the cause of the excellent fixation of the production process of dark neurons in experimental neuropathology in the reversibility of dark neurons.

Keywords : Central Nervous System, Dark Neurons, Experimental Neuropathology, Neurotransmitter, Protein Accumulation.